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专注多肽 服务科研
Lamin片段(核纤层蛋白片段)的多肽序列为Lys-Ala-Gly-Gln-Val-Val-Thr-Ile-Trp。
核纤层蛋白是V型中间丝,根据在细胞周期中的同源性序列、生物化学性质和细胞定位,可将其分为A型或B型,A型包括核纤层蛋白A和C,B型包括核纤层蛋白B1和B2。核纤层蛋白片段几乎涵盖了所有的α螺旋构象,由非α螺旋连接子分隔成多个α螺旋结构域,这些α螺旋结构域的氨基酸序列和长度高度保守。
核纤层蛋白是中间丝型的蛋白质,是核纤层的主要组成部分,核纤层是内核膜底层纤维状蛋白网络。核纤层蛋白也可以以弥漫性或斑点模式定位在细胞核内,在DNA复制、染色质组织、核孔复合体的空间排列、核生长以及核膜蛋白的锚固中发挥作用。
Peptide H-KAGQVVTIW-OH is a Research Peptide with significant interest within the field academic and medical research. Recent citations using H-KAGQVVTIW-OH include the following: Allopurinol non-covalently facilitates binding of unconventional peptides to HLA-B* 58: 01 X Huan, N Zhuo, HY Lee , EC Ren - Scientific Reports, 2023 - nature.comhttps://www.nature.com/articles/s41598-023-36293-z Rapid screening for the detection of HLA-B57 and HLA-B58 in prevention of drug hypersensitivity L Kostenko, L Kjer-Nielsen, I Nicholson - Tissue , 2011 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1111/j.1399-0039.2011.01649.x Development of a diagnostic test for the prediction and prevention of HLA-B57/B58-linked drug hypersensitivities L Kostenko - 2014 - minerva-access.unimelb.edu.auhttps://minerva-access.unimelb.edu.au/bitstream/handle/11343/51134/Combined-Thesis.pdf?sequence=1